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Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver;^[1][7] it is a type of viral hepatitis.^[8] It can cause both acute and chronic infection.^[1] Many people have no symptoms during the initial infection.^[1] In acute infection, some may develop a rapid onset of sickness with vomiting, yellowish skin, tiredness, dark urine, and abdominal pain.^[1] Often these symptoms last a few weeks and rarely does the initial infection result in death.^[1][9] It may take 30 to 180 days for symptoms to begin.^[1] In those who get infected around the time of birth 90% develop chronic hepatitis B while less than 10% of those infected after the age of five do.^[4] Most of those with chronic disease have no symptoms; however, cirrhosis and liver cancer may eventually develop.^[2] Cirrhosis or liver cancer occur in about 25% of those with chronic disease.^[1] 

 

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